Dr. Sandra Brogioni

Sandra Brogioni was born in Piombino on 1 February 1963.

In July 1982 she obtained the Classical High School Diploma at the Liceo Classico "Giosuè Carducci" in Piombino (LI). In December 1990 she graduated in Medicine and Surgery at the University of Pisa, with an experimental thesis entitled "The role of autoimmunity in hypothyroidism". On 12 November 1996 she obtained the Specialisation in "Endocrinology and Metabolic Diseases" at the University of Pisa with an experimental thesis entitled "Studies on the relationship between interleukin-6 and the thyroid", graded 50/50 with honours.

Since 1989 Dr. Sandra Brogioni has carried out basic and clinical research in the field of thyroid autoimmunity and thyroid physiology. In 1998 she obtained a scholarship working on the use of growth hormone in dilated cardiomyopathy. She is currently carrying out clinical research on pituitary disease and on thyroid disease due to iodine excess, in particular the molecular bases, pathogenesis, epidemiology and treatment of amiodarone-induced thyroid diseases.

Full member of the Italian Society of Endocrinology.

Currently Consultant physician (level I) at the Endocrinology II Unit, Pisa

-Bogazzi F, Ultimieri F, Raggi F, Russo D, Vanacore R, Guida C, Viacava P, Cecchetti D, Acerbi G, Brogioni S, Cosci C, Gasperi M, Bartalena L, Martino E. PPARgamma inhibits GH synthesis and secretion and increases apoptosis of pituitary GH-secreting adenomas. Eur J Endocrinol. 2004 Jun;150(6):863-75.

-Bogazzi F, Ultimieri F, Raggi F, Russo D, Vanacore R, Guida C, Brogioni S, Cosci C, Gasperi M, Bartalena L, Martino E. Growth hormone inhibits apoptosis in human colonic cancer cell lines: antagonistic effects of peroxisome proliferator activated receptor-gamma ligands. Endocrinology. 2004 Jul;145(7):3353-62.

-Bogazzi F, Ultimieri F, Raggi F, Russo D, Brogioni S, Cosci C, Gasperi M, Costa A, Viacava P, Mosca F, Bartalena L, Martino E. Colonic polyps of acromegalic patients are not associated with mutations of the peroxisome proliferator activated receptor gamma gene. J Endocrinol Invest. 2003 Nov;26(11):1054-8.

-Bogazzi F, Bartalena L, Campomori A, Brogioni S, Traino C, De Martino F, Rossi G, Lippi F, Pinchera A, Martino E. Treatment with lithium prevents serum thyroid hormone increase after thionamide withdrawal and radioiodine therapy in patients with Graves' disease. J Clin Endocrinol Metab. 2002 Oct;87(10):4490-5.

-Bogazzi F, Bartalena L, Brogioni S, Burelli A, Grasso L, Dell'Unto E, Manetti L, Martino E. L-thyroxine directly affects expression of thyroid hormone-sensitive genes: regulatory effect of RXRbeta. Mol Cell Endocrinol. 1997 Oct 31;134(1):23-31.

• Bartalena L, Brogioni S, Grasso L, Bogazzi F, Burelli A, Martino E. Treatment of amiodarone-induced thyrotoxicosis, a difficult challenge: results of a prospective study. J Clin Endocrinol Metab. 1996 Aug;81(8):2930-3.

Contacts

s.brogioni@yahoo.it